Exogenous Nitric Oxide Plays Important Roles in Wound Healing and has an Antibacterial Effect

  • Nam-Il Ji Department of Dermatology, Hospital of Chongjin College of Medical Sciences, Chongjin City
  • Kwang-Ho Choe MD Department of Dermatology, Hospital of Chongjin College of Medical Sciences, Chongjin City
  • Ju-Song Choe MD Department of Dermatology, Hospital of Pyongyang University of Medical Sciences, Pyongyang City
  • Sol-Hui Pak Department of Dermatology, Hospital of Pyongyang University of Medical Sciences, Pyongyang City
  • Chol Kim Department of Dermatology, Hospital of Chongjin College of Medical Sciences, Chongjin City
  • Yong-Sim Kwon Department of Plastic Surgery, Hospital of Pyongyang University of Medical Sciences
DOI: https://doi.org/10.5530/ijcep.2025.12.4.27
Keywords: Nitric oxide, Exogenous nitric oxide, Wound healing, Antibacterial effect, Plasma therapy, Experimental model

Abstract

Background and Aim: While air plasma has been widely used in biomedical or clinical applications, nitric oxide produced with plasma is thought to play important roles and be significant in biological activities. Our aim is to elucidate the role of exogenous nitric oxide in wound healing and antibacterial effect. Methods: 140 Wistar rats weighing 180 to 230 g were used. They were injured and irradiated by NO-containing plasma. Results: Wound healing was promoted in case of NO-containing plasma therapy. Conclusion: Exogenous nitric oxide prompts wound healing and has an antibacterial effect.

Published
2026-03-17
How to Cite
Ji, N.-I., MD, K.-H. C., MD, J.-S. C., Pak, S.-H., Kim, C., & Kwon, Y.-S. (2026). Exogenous Nitric Oxide Plays Important Roles in Wound Healing and has an Antibacterial Effect. International Journal of Clinical and Experimental Physiology, 12(4), 127-130. https://doi.org/10.5530/ijcep.2025.12.4.27
Issue
Vol 12 No 4 (2025): International Journal of Clinical and Experimental Physiology
Section
Original Article