Weight Loss Associated with Reduced Visceral Fat Deposition Mediated via Tea-induced Alterations in Adiponectin and Insulin Activities

Osah Martins Onwuka; Chimaobim Luke Okechukwu

doi:10.5530/ijcep.2022.9.1.7

Osah Martins Onwuka Department of Human Physiology, College of Medical and Health Sciences, Gregory University, Uturu-441103, Abia, NIGERIA.
Chimaobim Luke Okechukwu Department of Human Physiology, College of Medical and Health Sciences, Gregory University, Uturu-441103, Abia, NIGERIA.

DOI: https://doi.org/10.5530/ijcep.2022.9.1.7

Keywords: Adiponectin, Camellia sinensis, Insulin, Tea, Visceral fat deposition, Weight loss.

Abstract

Background and Aim: Weight decreasing potential of Lipton tea (product of camellia sinensis) was elucidated considering its impact on adiponectin and insulin concentration, which in turn influences the activities of adiponectin and insulin on their target cells. Hence this study was conducted forming tea nutritional basis for body weight and obesity control. Methods: Adiponectin, insulin, insulin resistance, free fatty acids, visceral fat depositions, body weight of male Wistar rats orally administered 200mg/kg, 400mg/kg, and 800mg/kg of Lipton tea as well as 500 mg/kg of metformin (a potent drug for weight loss) in various groups were measured to ascertain certain weight decreasing mechanism of Lipton tea. Results: Following the administration of Lipton tea for 28 days, it increased adiponectin and decreased insulin and insulin resistance, free fatty acids, visceral fats and body weight in a dose dependent manner when compared to control. Conclusion: Weight decreasing potential of Lipton tea via reduction in visceral fats is associated with increased adiponectin as well as decreased insulin concentration and decreased insulin resistance induced by the tea.