Anemia in Menstruating Women: Variation in Hematological Parameters in Different Phases of Menstrual Cycle

Abstract

Background and Aim: Menstrual cycle is a physiological process that occurs in women. It is characterized by periodic vaginal bleeding due to shedding of uterine mucosa. This has its own effect on various systems and metabolisms. This study was attempted to understand the variations in hematological parameters in different phases of menstrual cycle. Methods: The present study was conducted on 55 healthy female volunteers within the age group of 18 to 24 years having regular menstrual cycle of 28 ± 3 days from the female medical students of M. L. N. Medical College, Allahabad, U.P. We analyzed various hematological parameters on three different phases of menstrual cycle (Menstrual phase-2^nd day, Proliferative phase -12^th day and Secretory phase-22^nd day). Results: Regarding hematological parameters, the mean TLC and PMN count increased with time i.e. highest in secretory phase followed by proliferative phase and least in menstrual phase. In contrast, mean Hb was highest in proliferative phase followed by secretory phase and menstrual phase. Conversely, mean eosinophils level was highest in menstrual phase followed by secretory phase and least in proliferative phase. Conclusion: This study was a moderate attempt to determine regular variations in some specific hematological parameters, during different phases of menstrual cycle in normal healthy females and evaluate various changes and their association with women’s health. Eosinophil count increases in menstrual and premenstrual phase. In this phase exacerbation of menstrual asthma has also seen.