Combinative Effect of Red and Far-Infrared Laser Therapy on Histological Changes of Injured Muscle in Rats

International Journal of Clinical and Experimental Physiology

  • Ye Rim So1Postgraduate School, Pyongyang College of Medical Sciences, Taedonggang District, Pyongyang, DEMOCRATIC PEOPLE’S REPUBLIC OF KOREA.
  • Ryon Hui Choe1Postgraduate School, Pyongyang College of Medical Sciences, Taedonggang District, Pyongyang, DEMOCRATIC PEOPLE’S REPUBLIC OF KOREA.
  • Hyo Chol Pak1Postgraduate School, Pyongyang College of Medical Sciences, Taedonggang District, Pyongyang, DEMOCRATIC PEOPLE’S REPUBLIC OF KOREA.
  • Chung Hyok Jong2Postgraduate School, Pyongyang University of Medical Sciences, Central District, Pyongyang, DEMOCRATIC PEOPLE’S REPUBLIC OF KOREA.
  • Hyo Un Pak2Postgraduate School, Pyongyang University of Medical Sciences, Central District, Pyongyang, DEMOCRATIC PEOPLE’S REPUBLIC OF KOREA.
  • Sun Gum Kim2Postgraduate School, Pyongyang University of Medical Sciences, Central District, Pyongyang, DEMOCRATIC PEOPLE’S REPUBLIC OF KOREA.
  • Kwang Myong Jang3Sinuiju College of Medical Sciences, Phyonghwa-dong, Sinuiju, North Phyongan Province, DEMOCRATIC PEOPLE’S REPUBLIC OF KOREA.

Volume 12 Issue 3 Pages 111-114

DOI: 10.5530/ijcep.2025.12.3.23

Abstract

Background and Aim: The effects of red or far-infrared laser therapy are well known, but combinative effect of laser on muscle injury has not yet been investigated in experimental studies. Here, we aim to examine the combinative effect of red and far-infrared laser therapy in a rat muscle injury model. Methods: A total of male Wistar rats were randomly distributed into 3 groups: healthy Control Group (CG), untreated Muscle injury Group (MG) and combination of Red and Far-infrared laser therapy Group (RFG). Gastrocnemius injury in rat was induced by a single blunt-impact trauma based on previous studies. Laser therapy was started within 24 hr after muscle injury and applied every day for 21 days (1 min/day). Results: After combinative laser therapy (RFG), the area of damaged fibers, percentage in the area of collagen and leukocyte infiltration decreased significantly compared to MG. Conclusion: These results showed that the combination of Red and Far-infrared laser therapy was effective in muscle recovery and could modulate collagen and inflammatory process in injured muscle.

Keywords

  • Gastrocnemius Injury
  • Low-level laser therapy
  • Far-infrared laser therapy
International Journal of Clinical and Experimental Physiology

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