Myocardial works stress is linked to sympathovagal imbalance in prehypertensives
The link of sympathovagal imbalance (SVI) to rate‑pressure product (RPP), the marker of myocardial stress in prehypertension has not been elucidated. Body mass index (BMI), cardiovascular parameters, spectral analysis of heart rate variability, and RPP were assessed in young normotensives (n = 58) and prehypertensives (n = 58). BMI, heart rate, blood pressure, RPP and low‑frequency to high‑frequency (LF‑HF) ratio were more in prehypertensives compared to normotensives. Pearson correlation revealed a significant association of LF‑HF with RPP in prehypertensives, but not in normotensives. Bivariate regression analysis revealed the independent contribution of LF‑HF ratio to RPP in prehypertensives. It was concluded that SVI contributed to myocardial work stress in young prehypertensives.