Myocardial works stress is linked to sympathovagal imbalance in prehypertensives

  • Gopal Krushna Pal Departments of Physiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
  • Chandrasekaran Adithan Pharmacology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India
  • Jagadeeswaran Indumathy Departments of Physiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
  • Balasubramanian Suchitra Departments of Physiology and 1Pharmacology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Keywords: Myocardial work stress, prehypertension, sympathovagal imbalance

Abstract

The link of sympathovagal imbalance (SVI) to rate‑pressure product (RPP), the marker of myocardial stress in prehypertension has not been elucidated. Body mass index (BMI), cardiovascular parameters, spectral analysis of heart rate variability, and RPP were assessed in young normotensives (n = 58) and prehypertensives (n = 58). BMI, heart rate, blood pressure, RPP and low‑frequency to high‑frequency (LF‑HF) ratio were more in prehypertensives compared to normotensives. Pearson correlation revealed a significant association of LF‑HF with RPP in prehypertensives, but not in normotensives. Bivariate regression analysis revealed the independent contribution of LF‑HF ratio to RPP in prehypertensives. It was concluded that SVI contributed to myocardial work stress in young prehypertensives.

Published
2015-04-30
How to Cite
Pal, G. K., Adithan, C., Indumathy, J., & Suchitra, B. (2015). Myocardial works stress is linked to sympathovagal imbalance in prehypertensives. International Journal of Clinical and Experimental Physiology, 2(2), 134-136. Retrieved from http://ijcep.org/index.php/ijcep/article/view/77