Accelerated Renal Atherosclerosis in Congenital Nephrotic Syndrome: A Silent Fatal Inevitable Event

  • Majid Malaki Assistant Professor of Pediatric Nephrology, Pediatric Ward of Sevome Shaban Hospital, Tehran, IRAN.
Keywords: Atherosclerosis, Nephrotic, Accelerated, Proteinuria, Congenital, Infant

Abstract

Accelerated atherosclerosis and thrombosis can be common, rapid evolving as short as two years in consequence of severe proteinuria in infancy who had low reserve of thyroid hormone and hyperlipidemia. This case report recommends and insist on aggressive treatment of hypothyroidism and hyperlipidemia besides to albumin infusion and folic acid to prevent hyperhomocysteinemia due to hypothyroidism side effect. This case was an evidence that imbalance of serum albumin level as a porter of lipids and LDL level can be a predisposing factor for accelerated atherosclerosis in other organs needs to more investigation for approve.

An obstructed arteriole by thrombosis and thickening of medial layer thickness and inflammatory cell infiltration.
Published
2020-05-05
How to Cite
Malaki, M. (2020). Accelerated Renal Atherosclerosis in Congenital Nephrotic Syndrome: A Silent Fatal Inevitable Event. International Journal of Clinical and Experimental Physiology, 7(1), 38-39. https://doi.org/10.5530/ijcep.2020.7.1.10